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intriguingly, low-grade hyperketonemia (not leading to ketoacidosis, a rare, life-threatening side effect) may contribute to cardio-renal benefits and other effects, such as anti-inflammatory and antioxidant effects [188]

Curcumin penetration into the cerebral cortex and striatum was significantly enhanced, with delivery levels at 0.45 MPa acoustic pressure being 1.45-fold higher than at 0.31 MPa

Some early studies reported changes in delta activity or sleep organisation, but human findings were inconsistent and did not establish a reliable deep-sleep effect

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4,54 p73 turnover was also reportedly regulated by Pirh2, but not by COP1 or Mdm2